Objective To summarize the integrated rodent control measures in large-scale supermarkets by investigation and analysis of the cause of rodent damage therein. Methods The bait and trap methods were employed to capture rats for analysis of rodent palatability, density and population distribution. The powder trace method was used to evaluate the deratization effect. Results Rattus norvegicus was the predominant rodent species in large-scale supermarkets; apples were most palatable to the rats. The positive rate of rodent traces was 36.51% before the implementation of integrated control measures, and dropped to 0 after three months of rodent control, with a deratization effect of 100%. No rodent trace blocks were found in the following three consecutive months. Conclusion The integrated control measures were effective in rodent control.